Smoking is the foremost public health problem affecting the world and it has a crucial implication in causing many common diseases due to Helicobacter pylori infection which is globally distributed, smoking is considered as a critical risk factor that accelerates the infection with this bacterium, the study's goal was to find out how common Helicobacter pylori infections were among male cigarette and nargileh smokers. Blood samples were collected and used for detection of anti- Helicobacter pylori IgG Ab from 80 males who were smokers and 20 from non-smoker males.The prevalence of H. pylori positivity was 34% (24 (70.6%) in smokers and 10 (29.4%) in nonsmokers, The highest percentage (52.9%) was found in the young age group (25-34) years, and 88.2 % of H. pylori positive individuals exhibited stomach symptoms. Fifty percent (50%) of H. pylori-infected individuals were Nargilehsmokers. Smoking was a key factor in the seroprevalence of Helicobacter pylori and played a substantial impact on it.

Keywords— Helicobacter pylori, IgG, Cigarette, Nargileh, Smoker.

DOI: http://doi.org/10.24086/biohs2022/paper.623