Cihan University-Erbil Conferences, 4th International Conference on Biological & Health Sciences (CIC-BIOHS’2022)

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Interleukin-10 levels in relation to COVID-19 vaccine
Ameena Sabah Mahmood Juma

Last modified: 2022-08-30


The study was conducted in Cihan University-Erbil campus in November 2021. All subjects were asked questions regarding their history, using a questionnaire sheet. Blood was investigated for the Interleukin-10 level, Lactate Dehydrogenase (LDH) and hematological parameters. The mean serum level of IL-10 was significantly higher in Covid-19, non-vaccinated than Covid-19, vaccinated individuals. Moreover, the level was also equally significant and higher in non-Covid-19, vaccinated than non-Covid-19, non-vaccinated. Non-significant differences were found between Covid-19, vaccinated and non-Covid-19, non-vaccinated individuals. And between Covid-19, non-vaccinated and non-Covid-19, vaccinated individuals. The mean serum levels of LDH were found to be significantly lower in non-Covid-19, non-vaccinated, indicating a significant rise of LDH in all other groups. Despite the rise in all three groups a significant difference was not found between them. The total WBC count shows a significant increase in both non-vaccinated groups. While the mean level of lymphocytes counts reveals non-significant decrease in non-Covid-19, vaccinated group in comparison to the other groups. However, the mean monocyte counts of Covid-19, vaccinated group revealed a significant rise in comparison to other groups. In addition, the mean counts of granulocyte showed a significant increase in both non-vaccinated groups in comparison with vaccinated groups. Platelet mean count presented a non-significant difference when comparing all groups. Our current study may indicate the potency of the vaccines.


Keywords: Interleukin-10, COVID-19 Vaccine, Lactate Dehydrogenase (LDH) and hematological parameters.



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