Cihan University-Erbil Conferences, 4th International Conference on Biological & Health Sciences (CIC-BIOHS’2022)

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Determination of Antioxidant Property, Total Phenolics Content, and α-Glucosidase Inhibitory Activity of Different Solvent Extracts of Defatted and Non-Defatted Peanut Skins
Alkasim Kabiru Yunusa, Zahra'u B. Nouruddeen, Nura Abdullahi, Hafizu I. Kademi, Shamsuddeen S. Abubakar, Munir A. Dandago, Sarwan W. Bradosty, Abdurahman M. Dogara

Last modified: 2022-08-31

Abstract


Peanut skins are by-product with little economic value. The effect of different solvents, on the total phenolic content (TPC), antioxidant property and in vitro antidiabetic activity of defatted and non-defatted peanut skins was determined. TPC was estimated using Folin-Ciocalteau reagent. Antioxidant property was evaluated using ferric reducing antioxidant power (FRAP) and 2, 2-diphenyl-1- picrylhydrazyl (DPPH) radical scavenging capacity methods, α-glucosidase inhibition was evaluated using 4- nitrophenyl α-D-glucopyranoside (pNPG) method. Peanut skin of the defatted extracted with ethanol had the much of the content of total phenolics (391.76 mg/g GAE). Highest DPPH scavenging property was found in the methanolic extract of defatted peanut skins with IC50 value of 15.00 ± 1.00 μg/mL, while highest FRAP value was found in the aqueous extract of non-defatted extracts. Aqueous extracts demonstrated stronger inhibitory property against α-glucosidase and had IC50 of 16.33 ± 1.15 and 16.33 ± 8.50 μg/mL for defatted and non-defatted extracts, respectively. The finding of the present shows that peanut skins are important by-product for utilization as natural antioxidant and α-glucosidase inhibitors.

Keywords— Antioxidant, Extracts, Peanut skins, Solvent, α-glucosidase.

 

DOI: http://doi.org/10.24086/biohs2022/paper.781


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